human ARSB Over-expression AAV

Name
AAV-h-ARSB

Cat No
AAV-201485

Availability
4-5 weeks

This is an AAV expressing Human ARSB.

AAV-201485

AAV-h-ARSB

Ready-to-use AAV expressing Human ARSB (arylsulfatase B). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

ASB; G4S; MPS6

Description (Vector)

Arylsulfatase B encoded by this gene belongs to the sulfatase family. The arylsulfatase B homodimer hydrolyzes sulfate groups of N-Acetyl-D-galactosamine, chondriotin sulfate, and dermatan sulfate. The protein is targetted to the lysozyme. Mucopolysaccharidosis type VI is an autosomal recessive lysosomal storage disorder resulting from a deficiency of arylsulfatase B. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Gene ID

411

Gene Name (Vector)

arylsulfatase B

Gene Symbol

ARSB

HGNC ID

HGNC:714

ORF Size (aa)

1242

ORF Size (bp)

1242 bp

RefSeq ID

NM_000046

RefSeq Synonyms

NM_198709, NM_000046, BC029051,

Species

human

UniGene ID

Hs.604199

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.