human ANAPC7 Over-expression AAV

Name 
AAV-h-ANAPC7
Cat No 
AAV-201465
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human ANAPC7.

AAV-201465
AAV-h-ANAPC7

Ready-to-use AAV expressing Human ANAPC7 (anaphase promoting complex subunit 7). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
anaphase-promoting complex subunit 7; APC7; cyclosome subunit 7
Description (eCommerce)
Anaphase promoting complex subunit 7 (APC7) is a component of the APC/c (anaphase promoting complex/cyclosome) which is responsible for the ubiquitination and degradation of securin and cyclin B which prompts the onset of anaphase and exit from mitosis. The APC/c is composed of at least 11 subunits.
Description (Vector)
ANAPC7 encodes a tetratricopeptide repeat containing component of the anaphase promoting complex/cyclosome (APC/C), a large E3 ubiquitin ligase that controls cell cycle progression by targeting a number of cell cycle regulators such as B-type cyclins for 26S proteasome-mediated degradation through ubiquitination. The encoded protein is required for proper protein ubiquitination function of APC/C and for the interaction of APC/C with certain transcription coactivators. Multiple transcript variants encoding different isoforms have been found for this gene.
Gene ID
51434
Gene Name (eCommerce)
anaphase promoting complex subunit 7
Gene Name (Vector)
anaphase promoting complex subunit 7
Gene Symbol
ANAPC7
HGNC ID
HGNC:17380
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1698
ORF Size (bp)
1698 bp
Protein Name (eCommerce)
Anaphase-promoting complex subunit 7
RefSeq ID
NM_016238
RefSeq Synonyms
NM_016238, NM_001137664, BC148236, BC141848,
Research Areas
Antigen Processing and Presentation,Cell Cycle,Cell Division,Host-Virus Interactions,Immunology,Meiosis,Signal Transduction,TGF-beta Signaling,Ubiquitination
Research Areas (Faceted)
cell_biology,cell_cycle,developmental_biology,genetics,immunology,infectious_disease,signal_transduction
Species
human
Target Sentence
Anaphase promoting complex subunit 7 (APC7) is a component of the APC/c (anaphase promoting complex/cyclosome) which is responsible for the ubiquitination and degradation of securin and cyclin B which prompts the onset of anaphase and exit from mitosis. The APC/c is composed of at least 11 subunits.
UniGene ID
Hs.524741
UniProt ID (eCommerce)
Q9UJX3

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.