human AREG Over-expression AAV

Name 
AAV-h-AREG
Cat No 
AAV-201262
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human AREG.

AAV-201262
AAV-h-AREG

Ready-to-use AAV expressing Human AREG (amphiregulin). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
AR; AREGB; CRDGF; SDGF
Description (Vector)
AREG is a member of the epidermal growth factor family. It is an autocrine growth factor as well as a mitogen for astrocytes, Schwann cells, and fibroblasts. It is related to epidermal growth factor (EGF) and transforming growth factor alpha (TGF-alpha). This protein interacts with the EGF/TGF-alpha receptor to promote the growth of normal epithelial cells and inhibits the growth of certain aggressive carcinoma cell lines. This encoded protein is associated with a psoriasis-like skin phenotype.
Gene ID
374
Gene Name (Vector)
amphiregulin
Gene Symbol
AREG
HGNC ID
HGNC:651
ORF Size (aa)
759
ORF Size (bp)
759 bp
RefSeq ID
NM_001657
RefSeq Synonyms
NM_001657, BC146967, BC146953, BC009799,
Species
human
UniGene ID
Hs.270833

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.