human APOL1 Over-expression AAV

Name 
AAV-h-APOL1
Cat No 
AAV-201203
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human APOL1.

AAV-201203
AAV-h-APOL1

Ready-to-use AAV expressing Human APOL1 (apolipoprotein L1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
APO-L; APOL; APOL-I; FSGS4
Description (Vector)
APOL1 encodes a secreted high density lipoprotein which binds to apolipoprotein A-I. Apolipoprotein A-I is a relatively abundant plasma protein and is the major apoprotein of HDL. It is involved in the formation of most cholesteryl esters in plasma and also promotes efflux of cholesterol from cells. This apolipoprotein L family member may play a role in lipid exchange and transport throughout the body, as well as in reverse cholesterol transport from peripheral cells to the liver. Several different transcript variants encoding different isoforms have been found for this gene.
Gene ID
8542
Gene Name (Vector)
apolipoprotein L1
Gene Symbol
APOL1
HGNC ID
HGNC:618
ORF Size (aa)
1197
ORF Size (bp)
1197 bp
RefSeq ID
NM_003661
RefSeq Synonyms
NM_145343, NM_003661, NM_001136541, NM_001136540, BC143039, BC143038, BC141823, BC127186, BC112943,
Species
human
UniGene ID
Hs.114309

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.