human ANGPTL3 Over-expression AAV

Name 
AAV-h-ANGPTL3
Cat No 
AAV-200918
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human ANGPTL3.

AAV-200918
AAV-h-ANGPTL3

Ready-to-use AAV expressing Human ANGPTL3 (angiopoietin like 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
ANG-5; ANGPT5; ANL3; FHBL2
Description (Vector)
ANGPTL3 is a member of the angiopoietin-like family of secreted factors. It is predominantly expressed in the liver, and has the characteristic structure of angiopoietins, consisting of a signal peptide, N-terminal coiled-coil domain and the C-terminal fibrinogen (FBN)-like domain. The FBN-like domain in angiopoietin-like 3 protein was shown to bind alpha-5/beta-3 integrins, and this binding induced endothelial cell adhesion and migration. This protein may also play a role in the regulation of angiogenesis.
Gene ID
27329
Gene Name (Vector)
angiopoietin like 3
Gene Symbol
ANGPTL3
HGNC ID
HGNC:491
ORF Size (aa)
1383
ORF Size (bp)
1383 bp
RefSeq ID
NM_014495
RefSeq Synonyms
NM_014495, BC058287,
Species
human
UniGene ID
Hs.209153

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.