human ALDH8A1 Over-expression AAV

Name 
AAV-h-ALDH8A1
Cat No 
AAV-200749
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human ALDH8A1.

AAV-200749
AAV-h-ALDH8A1

Ready-to-use AAV expressing Human ALDH8A1 (aldehyde dehydrogenase 8 family member A1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
ALDH12; DJ352A20.2
Description (Vector)
This protein belongs to the aldehyde dehydrogenases family of proteins. It plays a role in a pathway of 9-cis-retinoic acid biosynthesis in vivo. This enzyme converts 9-cis-retinal into the retinoid X receptor ligand 9-cis-retinoic acid, and has approximately 40-fold higher activity with 9-cis-retinal than with all-trans-retinal. Therefore, it is the first known aldehyde dehydrogenase to show a preference for 9-cis-retinal relative to all-trans-retinal. Three transcript variants encoding distinct protein isoforms have been identified for this gene.
Gene ID
64577
Gene Name (Vector)
aldehyde dehydrogenase 8 family member A1
Gene Symbol
ALDH8A1
HGNC ID
HGNC:15471
ORF Size (aa)
798
RefSeq ID
NM_022568
RefSeq Synonyms
NM_170771, NM_022568, NM_001193480, BC114473, BC113862,
Species
human
UniGene ID
Hs.486520

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.