human ALDH6A1 Over-expression AAV

Name
AAV-h-ALDH6A1

Cat No
AAV-200744

Availability
4-5 weeks

This is an AAV expressing Human ALDH6A1.

AAV-200744

AAV-h-ALDH6A1

Ready-to-use AAV expressing Human ALDH6A1 (aldehyde dehydrogenase 6 family member A1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

MMSADHA; MMSDH

Description (Vector)

This protein belongs to the aldehyde dehydrogenases family of proteins. This enzyme plays a role in the valine and pyrimidine catabolic pathways. The product of this gene, a mitochondrial methylmalonate semialdehyde dehydrogenase, catalyzes the irreversible oxidative decarboxylation of malonate and methylmalonate semialdehydes to acetyl- and propionyl-CoA. Methylmalonate semialdehyde dehydrogenase deficiency is characterized by elevated beta-alanine, 3-hydroxypropionic acid, and both isomers of 3-amino and 3-hydroxyisobutyric acids in urine organic acids.

Gene ID

4329

Gene Name (Vector)

aldehyde dehydrogenase 6 family member A1

Gene Symbol

ALDH6A1

HGNC ID

HGNC:7179

ORF Size (aa)

1608

ORF Size (bp)

1608 bp

RefSeq ID

NM_005589

RefSeq Synonyms

NM_005589, NM_001278594, NM_001278593, BC032371, BC004909,

Species

human

UniGene ID

Hs.293970

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.