human ALDH4A1 Over-expression AAV

Name
AAV-h-ALDH4A1

Cat No
AAV-200741

Availability
4-5 weeks

This is an AAV expressing Human ALDH4A1.

AAV-200741

AAV-h-ALDH4A1

Ready-to-use AAV expressing Human ALDH4A1 (aldehyde dehydrogenase 4 family member A1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

ALDH4; P5CD; P5CDh

Description (Vector)

This protein belongs to the aldehyde dehydrogenase family of proteins. This enzyme is a mitochondrial matrix NAD-dependent dehydrogenase which catalyzes the second step of the proline degradation pathway, converting pyrroline-5-carboxylate to glutamate. Deficiency of this enzyme is associated with type II hyperprolinemia, an autosomal recessive disorder characterized by accumulation of delta-1-pyrroline-5-carboxylate (P5C) and proline. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.

Gene ID

8659

Gene Name (Vector)

aldehyde dehydrogenase 4 family member A1

Gene Symbol

ALDH4A1

HGNC ID

HGNC:406

ORF Size (aa)

1692

ORF Size (bp)

1692 bp

RefSeq ID

NM_170726

RefSeq Synonyms

NM_170726, NM_003748, NM_001319218, NM_001161504, BC023600, BC007581,

Species

human

UniGene ID

Hs.77448

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.