human ALDH3A1 Over-expression AAV

Name 
AAV-h-ALDH3A1
Cat No 
AAV-200734
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human ALDH3A1.

AAV-200734
AAV-h-ALDH3A1

Ready-to-use AAV expressing Human ALDH3A1 (aldehyde dehydrogenase 3 family member A1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
ALDH3; ALDHIII
Description (Vector)
Aldehyde dehydrogenases oxidize various aldehydes to the corresponding acids. They are involved in the detoxification of alcohol-derived acetaldehyde and in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation. The enzyme encoded by this gene forms a cytoplasmic homodimer that preferentially oxidizes aromatic and medium-chain (6 carbons or more) saturated and unsaturated aldehyde substrates. It is thought to promote resistance to UV and 4-hydroxy-2-nonenal-induced oxidative damage in the cornea. The gene is located within the Smith-Magenis syndrome region on chromosome 17. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Gene ID
218
Gene Name (Vector)
aldehyde dehydrogenase 3 family member A1
Gene Symbol
ALDH3A1
HGNC ID
HGNC:405
ORF Size (aa)
1362
ORF Size (bp)
1362 bp
RefSeq ID
NM_000691
RefSeq Synonyms
NM_001330150, NM_001135168, NM_001135167, NM_000691, BC021194, BC008892, BC004370,
Species
human
UniGene ID
Hs.531682

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.