human AKR7A2 Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-200694
Availability:
3-5 weeks
Name:
AAV-h-AKR7A2
This is an AAV expressing Human AKR7A2.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- AKR7A2
- Gene Name
- aldo-keto reductase family 7 member A2
- Gene ID
- 8574
- Gene Synonyms
- AFAR; AFAR1; AFB1-AR1; AKR7
- ORF Size
- 993 bp
- RefSeq#
- BC012171
- Gene Description
- AKR7A2 belongs to the aldo/keto reductase (AKR) superfamily and AKR7 family, which are involved in the detoxification of aldehydes and ketones. The AKR7 family consists of 3 genes that are present in a cluster on the p arm of chromosome 1. This protein, thought to be localized in the golgi, catalyzes the NADPH-dependent reduction of succinic semialdehyde to the endogenous neuromodulator, gamma-hydroxybutyrate. It may also function as a detoxication enzyme in the reduction of aflatoxin B1 and 2-carboxybenzaldehyde.
- UniGene ID
- Hs.571886
- HGNC ID
- HGNC:389
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