human AGTR2 Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-200583
Availability:
3-5 weeks
Name:
AAV-h-AGTR2
This is an AAV expressing Human AGTR2.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- AGTR2
- Gene Name
- angiotensin II receptor type 2
- Gene ID
- 186
- Gene Synonyms
- AT2; ATGR2; MRX88
- ORF Size
- 1092 bp
- RefSeq#
- BC095504
- Gene Description
- AGTR2 belongs to the G-protein coupled receptor 1 family, and functions as a receptor for angiotensin II. It is an intergral membrane protein that is highly expressed in fetus, but scantily in adult tissues, except brain, adrenal medulla, and atretic ovary. This receptor has been shown to mediate programmed cell death and this apoptotic function may play an important role in developmental biology and pathophysiology. Mutations in this gene are been associated with X-linked mental retardation.
- UniGene ID
- Hs.405348
- HGNC ID
- HGNC:338
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