human AGPAT2 Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-200568
Availability:
3-5 weeks
Name:
AAV-h-AGPAT2
This is an AAV expressing Human AGPAT2.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- AGPAT2
- Gene Name
- 1-acylglycerol-3-phosphate O-acyltransferase 2
- Gene ID
- 10555
- Gene Synonyms
- 1-AGPAT2; BSCL; BSCL1; LPAAB; LPAAT-beta
- ORF Size
- 840 bp
- RefSeq#
- BC019292
- Gene Description
- AGPAT2 encodes a member of the 1-acylglycerol-3-phosphate O-acyltransferase family. The protein is located within the endoplasmic reticulum membrane and converts lysophosphatidic acid to phosphatidic acid, the second step in de novo phospholipid biosynthesis. Mutations in this gene have been associated with congenital generalized lipodystrophy (CGL), or Berardinelli-Seip syndrome, a disease characterized by a near absence of adipose tissue and severe insulin resistance. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
- UniGene ID
- Hs.320151
- HGNC ID
- HGNC:325
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