human ADRA1B Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-200499
Availability:
3-5 weeks
Name:
AAV-h-ADRA1B
This is an AAV expressing Human ADRA1B.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- ADRA1B
- Gene Name
- adrenoceptor alpha 1B
- Gene ID
- 147
- Gene Synonyms
- ADRA1; ALPHA1BAR
- ORF Size
- 1563 bp
- RefSeq#
- BC136569
- Gene Description
- Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1B-adrenergic receptor, which induces neoplastic transformation when transfected into NIH 3T3 fibroblasts and other cell lines. Thus, this normal cellular gene is identified as a protooncogene. This gene comprises 2 exons and a single large intron of at least 20 kb that interrupts the coding region.
- UniGene ID
- Hs.368632
- HGNC ID
- HGNC:278
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