human ACOX1 Over-expression AAV

Name
AAV-h-ACOX1

Cat No
AAV-200219

Availability
4-5 weeks

This is an AAV expressing Human ACOX1.

AAV-200219

AAV-h-ACOX1

Ready-to-use AAV expressing Human ACOX1 (acyl-CoA oxidase 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

ACOX; PALMCOX; SCOX

Description (Vector)

ACOX1 is the first enzyme of the fatty acid beta-oxidation pathway, which catalyzes the desaturation of acyl-CoAs to 2-trans-enoyl-CoAs. It donates electrons directly to molecular oxygen, thereby producing hydrogen peroxide. Defects in this gene result in pseudoneonatal adrenoleukodystrophy, a disease that is characterized by accumulation of very long chain fatty acids. Alternatively spliced transcript variants encoding different isoforms have been identified.

Gene ID

Gene Name (Vector)

acyl-CoA oxidase 1

Gene Symbol

ACOX1

HGNC ID

HGNC:119

ORF Size (aa)

1983

ORF Size (bp)

1983 bp

RefSeq ID

NM_004035

RefSeq Synonyms

NM_007292, NM_004035, NM_001185039, BC010425, BC008767,

Species

human

UniGene ID

Hs.464137

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.