human ABI3 Over-expression AAV

Name
AAV-h-ABI3

Cat No
AAV-200125

Availability
4-5 weeks

This is an AAV expressing Human ABI3.

AAV-200125

AAV-h-ABI3

Ready-to-use AAV expressing Human ABI3 (ABI family member 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

NESH; SSH3BP3

Description (Vector)

ABI3 encodes a member of an adaptor protein family. Members of this family encode proteins containing a homeobox homology domain, proline rich region and Src-homology 3 (SH3) domain, and are components of the Abi/WAVE complex which regulates Rac-dependent actin polymerization. The encoded protein inhibits ectopic metastasis of tumor cells as well as cell migration. This may be accomplished through interaction with p21-activated kinase.

Gene ID

51225

Gene Name (Vector)

ABI family member 3

Gene Symbol

ABI3

HGNC ID

HGNC:29859

ORF Size (aa)

1101

ORF Size (bp)

1101 bp

RefSeq ID

NM_016428

RefSeq Synonyms

NM_016428, NM_001135186, BC007780,

Species

human

UniGene ID

Hs.130719

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.