human ABCB8 Over-expression AAV

Name 
AAV-h-ABCB8
Cat No 
AAV-200063
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human ABCB8.

AAV-200063
AAV-h-ABCB8

Ready-to-use AAV expressing Human ABCB8 (ATP binding cassette subfamily B member 8). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
EST328128; M-ABC1; MABC1
Description (Vector)
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. The function of this half-transporter has not yet been determined; however, it may involve the compartmentalization and transport of heme, as well as peptides, from the mitochondria to the nucleus and cytosol. This protein may also play a role in the transport of phospholipids into mitochondrial membranes.
Gene ID
11194
Gene Name (Vector)
ATP binding cassette subfamily B member 8
Gene Symbol
ABCB8
HGNC ID
HGNC:49
ORF Size (aa)
2157
ORF Size (bp)
2157 bp
RefSeq ID
NM_007188
RefSeq Synonyms
NM_007188, NM_001282293, NM_001282292, NM_001282291, BC151235, BC146829, BC143080, BC141836, BC141814,
Species
human
UniGene ID
Hs.647118

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.