human A2BP1 Over-expression AAV

Name 
AAV-h-A2BP1
Cat No 
AAV-200005
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human RBFOX1.

AAV-200005
AAV-h-A2BP1

Ready-to-use AAV expressing Human RBFOX1 (RNA binding protein, fox-1 homolog 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
2BP1; A2BP1; FOX-1; FOX1; HRNBP1
Description (Vector)
The Fox-1 family of RNA-binding proteins is evolutionarily conserved, and regulates tissue-specific alternative splicing in metazoa. Fox-1 recognizes a (U)GCAUG stretch in regulated exons or in flanking introns. The protein binds to the C-terminus of ataxin-2 and may contribute to the restricted pathology of spinocerebellar ataxia type 2 (SCA2). Ataxin-2 is the product of the SCA2 gene which causes familial neurodegenerative diseases. Fox-1 and ataxin-2 are both localized in the trans-Golgi network. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Gene ID
54715
Gene Name (Vector)
RNA binding protein, fox-1 homolog 1
Gene Symbol
RBFOX1
HGNC ID
HGNC:18222
ORF Size (aa)
1188
ORF Size (bp)
1188 bp
RefSeq ID
NM_145891
RefSeq Synonyms
NM_145893, NM_145892, NM_145891, NM_018723, NM_001308117, NM_001142334, NM_001142333, BC113691,
Species
human
UniGene ID
Hs.459842

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.