human CD31 shRNA Adenovirus
This is an pre-made gene silencing adenovirus that expresses a shRNA to knockdown human CD31 gene. The shRNA expression is driven by an U6 promoter.
The knockdown of this human gene was validated by qPCR in HUVEC cells.
1821
Ad-h-CD31-shRNA
Ready-to-use human CD31 shRNA Adenovirus. human CD31 shRNA adenovirus gene knockdown1821
Gene Reference Data
Alternate Names
CD antigen CD31; CD31; CD31 antigen; CD31/EndoCAM; endoCAM; GPIIA'; PECA1; PECAM-1; platelet endothelial cell adhesion molecule; platelet endothelial cell adhesion molecule-1
Description (eCommerce)
CD31 is a cell adhesion molecule expressed mainly in platelets, endothelial cells, and a subset of leukocytes. CD31 localizes to cell-cell junctions and functions as a signaling molecule involved in a variety of vascular-related processes such as angiogenesis, platelet function, and inflammation.
Description (Vector)
PECAM1 is found on the surface of platelets, monocytes, neutrophils, and some types of T-cells, and makes up a large portion of endothelial cell intercellular junctions. The encoded protein is a member of the immunoglobulin superfamily and is likely involved in leukocyte migration, angiogenesis, and integrin activation.
Gene ID
5175
Gene Name (eCommerce)
platelet and endothelial cell adhesion molecule 1
Gene Name (Vector)
platelet and endothelial cell adhesion molecule 1
Gene Symbol
PECAM1
HGNC ID
HGNC:8823
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2217
ORF Size (bp)
2217 bp
Protein Name (eCommerce)
Platelet endothelial cell adhesion molecule
RefSeq ID
NM_000442
RefSeq Synonyms
NM_000442, BC051822, BC022512,
Research Areas
Cardiovascular,Immunology,Signal Transduction,T-cell Receptor Signaling
Research Areas (Faceted)
cardiovascular,immunology,signal_transduction
Species
human
Target Sentence
CD31 is a cell adhesion molecule expressed mainly in platelets, endothelial cells, and a subset of leukocytes. CD31 localizes to cell-cell junctions and functions as a signaling molecule involved in a variety of vascular-related processes such as angiogenesis, platelet function, and inflammation.
UniGene ID
Hs.514412
UniProt ID (eCommerce)
P16284
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.