human CASP7 shRNA Adenovirus
This is an pre-made gene silencing adenovirus that expresses a shRNA to knockdown human CASP7 gene. The shRNA expression is driven by an U6 promoter.
The knockdown of this human gene was validated by western blot in A549 cells.
1817
Ad-h-CASP7-shRNA
Ready-to-use human CASP7 shRNA Adenovirus. human CASP7 shRNA adenovirus gene knockdown1817
Gene Reference Data
Alternate Names
CASP-7; CMH-1; ICE-LAP3; LICE2; MCH3
Description (Vector)
CASP7 encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The precursor of the encoded protein is cleaved by caspase 3 and 10, is activated upon cell death stimuli and induces apoptosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Gene ID
840
Gene Name (Vector)
caspase 7
Gene Symbol
CASP7
HGNC ID
HGNC:1508
ORF Size (aa)
912
ORF Size (bp)
912 bp
RefSeq ID
NM_001227
RefSeq Synonyms
NM_033340, NM_033339, NM_033338, NM_001320911, NM_001267058, NM_001267057, NM_001267056, NM_001227, BC015799,
Species
human
UniGene ID
Hs.9216
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.