human BIRC3 shRNA Adenovirus
This is an pre-made gene silencing adenovirus that expresses a shRNA to knockdown human BIRC3 gene. The shRNA expression is driven by an U6 promoter.
The knockdown of this human gene was validated by qPCR in A549 cells.
1813
Ad-h-BIRC3-shRNA
Ready-to-use human BIRC3 shRNA Adenovirus. human BIRC3 shRNA adenovirus gene knockdown1813
Gene Reference Data
Alternate Names
AIP1; API2; c-IAP2; CIAP2; HAIP1; HIAP1; MALT2; MIHC; RNF49
Description (Vector)
BIRC3 encodes a member of the IAP family of proteins that inhibit apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. The encoded protein inhibits apoptosis induced by serum deprivation but does not affect apoptosis resulting from exposure to menadione, a potent inducer of free radicals. It contains 3 baculovirus IAP repeats and a ring finger domain. Transcript variants encoding the same isoform have been identified.
Gene ID
330
Gene Name (Vector)
baculoviral IAP repeat containing 3
Gene Symbol
BIRC3
HGNC ID
HGNC:591
ORF Size (aa)
1815
ORF Size (bp)
1815 bp
RefSeq ID
NM_001165
RefSeq Synonyms
NM_182962, NM_001165, BC037420,
Species
human
UniGene ID
Hs.127799
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.