AP1-Luc Adenovirus
Expression of the Photinus pyralis (firefly) luciferase gene is controlled by a synthetic promoter that contains direct repeats of the transcription recognition sequences for the activator protein 1 (AP1).
When this Luciferase reporter adenovirus and an uncharacterized gene are cotransfected into mammalian cells, the activation of endogenous protein kinases initiated by the cotransfected gene product will result in the activation of corresponding trans-activators which in turn stimulate luciferasae expression.
1670
Ad-AP1-Luc
Ready-to-use AP1-Luc Adenovirus. Ad-AP1-Luc 1670
Related Citations
- Visfatin induces stromal cell-derived factor-1 expression by ß1 integrin signaling in colorectal cancer cells. Wen-Shih Huang, etc, (2012), Journal of Cellular Physiology
- Regulation of cyclooxygenase-2 expression in human bladder epithelial cells infected with type I fimbriated Uropathogenic E. coli. Chen TC, etc, (2011), Cell Microbiol
- An essential role of PDCD4 in vascular smooth muscle cell apoptosis and proliferation: implications for vascular disease. Xiaojun Liu, (2010), Am J Physiol Cell Physiol
- Interleukin-18 induces EMMPRIN expression in primary cardiomyocytes via JNK/Sp1 signaling and MMP-9 in part via EMMPRIN and through AP-1 and NF-kappaB activation. Reddy VS. etc, (2010), Am J Physiol Heart Circ Physiol
- Involvement Of Micrornas In Hydrogen Peroxide-Mediated Gene Regulation And Cellular Injury Response In Vascular Smooth Muscle Cells. Lin Y, etc, (2009), J. Biol. Chem
- Microrna Expression Signature And The Role Of Microrna-21 In The Early Phase Of Acute Myocardial Infarction. Dong S, etc, (2009), J. Biol. Chem
- Microrna-21 Protects Against The H2o2-Induced Injury On Cardiac Myocytes Via Its Target Gene Pdcd4. Cheng, YH. etc, (2009), Journal of Molecular and Cellular Cardiology
- Il-17 Stimulates MMP-1 Expression In Primary Human Cardiac Fibroblasts Via P38 Mapk- And Erk1/2-Dependent C/Ebp-ß, Nf-{Kappa}B, And Ap-1 Activation. Cortez, D., etc., (2007), Am J Physiol Heart Circ Physiol
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.