NOGO Receptor Adenovirus
The Nogo receptor is a brain-specific protein that is most highly expressed in the gray matter of the CNS. Nogo-R binds with high affinity to the extracellular domain of Nogo, a component of CNS white matter that prevents axonal regeneration in the adult CNS. Binding of Nogo-R to Nogo is sufficient to elicit Nogo axonal inhibition to unresponsive neurons. Disruption of the interaction between Nogo and its receptor may provide for enhanced recovery after human CNS injury.
1584
Ad-NOGO-R
Ready-to-use NOGO Receptor Adenovirus. Ad-NOGO-R, NOGO Receptor, NGR, NOGOR, RTN4R, NOGO-R, NOGO-66-R, NOGO66-R, NOGO Receptor adenovirus 1584
Gene Reference Data
Alternate Names
NGR; NOGOR
Description (Vector)
RTN4R encodes the receptor for reticulon 4, oligodendrocyte myelin glycoprotein and myelin-associated glycoprotein. This receptor mediates axonal growth inhibition and may play a role in regulating axonal regeneration and plasticity in the adult central nervous system.
Gene ID
65078
Gene Name (Vector)
reticulon 4 receptor
Gene Symbol
RTN4R
HGNC ID
HGNC:18601
ORF Size (aa)
1422
ORF Size (bp)
1422 bp
RefSeq ID
NM_023004
RefSeq Synonyms
NM_023004, BC011787,
Species
human
UniGene ID
Hs.30868
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.