Plasminogen activator inhibitor-2 / serpin peptidase inhibitor, clade B (ovalbumin), member 2 Adenovirus

Name 
Ad-PAI-2
Cat No 
1580
Availability
Immediate

PAI-1 and PAI-2 (plasminogen activator inhibitor-1 and -2) are members of the serpin serine proteinase inhibitor family. PAI-1 and PAI-2 regulate uPA (urokinase-type plasminogen activator) and TPA (tissue plasminogen activator), resulting in the inhibition of proteolytic activity. Members of the serpin family generally complex with their target proteinases, then disassociate slowly into cleaved species that fold into stable inactive forms. PAI-1 can fold into the inactive state without cleavage resulting in the latent form of PAI-1. Activity can be restored to the latent form of PAI-1 through denaturation and renaturation. PAI-2 occurs in secreted and cytosolic forms through facultative polypeptide translocation.

1580
Ad-PAI-2

Ready-to-use Plasminogen activator inhibitor-2 / serpin peptidase inhibitor, clade B (ovalbumin), member 2 Adenovirus. Ad-PAI-2, “Plasminogen activator inhibitor-2 / serpin peptidase inhibitor, clade B (ovalbumin), member 2”, PAI, PAI2, PAI-2, PLANH2, HST1201, SERPINB2, SERPINE B2 adenovirus 1580

$690.00
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Product Details

Promoter
CMV (ubiquitous)
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Titer
1x10^10 PFU/ml
Viral Backbone
Human Adenovirus Type5 (dE1/E3)
Volume (µL)
200

Gene Reference Data

Alternate Names
HsT1201; PAI; PAI-2; PAI2; PLANH2
Gene ID
5055
Gene Name (Vector)
serpin family B member 2
Gene Symbol
SERPINB2
HGNC ID
HGNC:8584
ORF Size (aa)
1248
ORF Size (bp)
1248 bp
RefSeq ID
NM_002575
RefSeq Synonyms
NM_002575, NM_001143818, BC012609,
Species
human
UniGene ID
Hs.594481

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.