PPARdelta Adenovirus

Name 
Ad-PPARd
Cat No 
1284
Availability
Immediate
Categories
Adenovirus, Over-Expression

Peroxisome proliferator-activated receptor delta (PPARd) belongs to the nuclear receptor superfamily, which includes the steroid hormone, thyroid hormone, retinoid, and PPAR subfamilies as well as a growing number of orphan receptors. They function as ligand-dependent sequence-specific activators of transcription. When the PPAR is activated, transcription is increased. However, PPAR can also suppress a number of genes. The function of PPARs depends on the shape of their ligand-binding domain and their co-activators and co-repressors. Ligands for the PPARs include free fatty acids and eicosanoids.

Three types of PPARs have been identified: alpha, gamma and delta. PPARd, identical to PPARb, is expressed in many tissues but markedly in brain, adipose tissue and skin. All PPARs dimerize with the retinoid X-receptor (RXR) and bind to PPREs (peroxisome proliferator response elements), which generally occurs in the promoter region of a gene. The GFP tagged to PPARd will allow the determination of the amount and location of PPARd expression.

This adenovirus contain PPARdelta with GFP.

Reference: He TC., et al., Cell. 1999 Oct 29;99(3):335-45.

1284
Ad-PPARd

Ready-to-use PPARdelta Adenovirus. PPARd PPARb adenovirus PPARdelta Peroxisome proliferator-activated receptor delta 1284

$475.00
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Product Details

Reporter
eGFP
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Titer
1x10^10 PFU/ml
Viral Backbone
Human Adenovirus Type5 (dE1/E3)
Volume (µL)
200

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.