Three types of PPARs have been identified: alpha, gamma and delta. PPARd, identical to PPARb, is expressed in many tissues but markedly in brain, adipose tissue and skin. All PPARs dimerize with the retinoid X-receptor (RXR) and bind to PPREs (peroxisome proliferator response elements), which generally occurs in the promoter region of a gene. The GFP tagged to PPARd will allow the determination of the amount and location of PPARd expression.
This adenovirus contain PPARdelta with GFP.
Reference: He TC., et al., Cell. 1999 Oct 29;99(3):335-45.
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- Viral Backbone
- Human Adenovirus Type5 (dE1/E3)
- Storage Buffer
- DMEM, 2% BSA, 2.5% Glycerol
- 1x10^10 PFU/ml