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Why Use AAV or Adenovirus
AAV and adenoviruses are powerful gene delivery tools and are similar in that both integrate into the host cell episomally.
AAV
Adenovirus
Gene Expression
Long-term, stable expression
Rapid, transient expression
Immunogenicity
Low
High
Payload Capacity
~4.7kb
~8kb-38kb (much larger)
Tropism (Targeting Ability)
High - tailored with different capsids
Broad targeting across many tissues
Best used for
In-vivo studies, long-term expression
In-vitro & in-vivo, cancer & vaccine research
Feature |
AAV |
Adenovirus |
|---|---|---|
Gene Expression
| ||
Immunogenicity
| ||
Payload Capacity
| ||
Tropism (Targeting ability)
| ||
Best used for |
In-vivo studies, long-term expression | In-vitro & in-vivo, cancer & vaccine research |
AAV Custom Production
Create tailored solutions with our AAV custom production services, offering flexibility and precision for your projects.
AAV Control Products
Achieve consistent results with our expertly validated AAV control products for rigorous experimental standards.
Visit PageAAV Product Catalog
Browse our extensive AAV product catalog, featuring a wide range of vectors designed for diverse research goals.
Visit PageAdenovirusConstruction
Adenovirus control products ensure accuracy and reliability in gene delivery and molecular studies.
Visit PageAdenovirus Amplification
Adenovirus control products ensure accuracy and reliability in gene delivery and molecular studies.
Visit PageAdenovirus Control Products
Adenovirus control products ensure accuracy and reliability in gene delivery and molecular studies.
Visit PageAdenovirus Products Catalog
Adenovirus control products ensure accuracy and reliability in gene delivery and molecular studies.
Visit Page
Product Differentiation
AAV
What is Adeno-Associated Virus (AAV)?
Adeno-Associated Virus (AAV) is a safe, non-pathogenic virus used for gene delivery in research and therapy.
It effectively targets diverse tissues, providing long-term gene expression with minimal risk of genetic mutations.
Adenovirus
What is Adenovirus?
Adenovirus is a robust viral vector capable of delivering large genes, ideal for various research and therapy uses. It infects a wide range of cell types and provides high short-term gene expression.
AAV
Adenovirus
Tropism
Dividing and Non-Dividing Cells
Dividing and Non-Dividing Cells
Genome Integration
No
No
Packaging Capacity
~4.5 kb
~8.5 kb
Protein Expression
Low
High
Gene Expression
Potentially Long Lasting
Transient
Target Cell’s Immune Response
Low
Low
Onset of Expression
2-7 Days (in vitro)
3-21 Days (in vivo)
3-21 Days (in vivo)
16-24 Hours
Biosafety Level
BSL-1
BSL-2
Characteristic |
AAV |
Adenovirus |
|---|---|---|
Tropism |
Dividing and Non-Dividing Cells | Dividing and Non-Dividing Cells |
Genome Integration |
No | No |
Packaging Capacity |
~4.5 kb | ~8.5 kb |
Protein Expression |
Low | High |
Gene Expression |
Potentially Long Lasting | Transient |
Target Cell’s Immune Response |
Low | High |
Onset of Expression |
2-7 Days (in vitro), 3-21 Days (in vivo) | 16-24 Hours |
Biosafety Level |
BSL-1 | BSL-2 |
AAV
Gene Therapy
Efficiently delivers therapeutic genes for long-term treatment of genetic disorders.
Gene Editing
Used to deliver CRISPR-Cas9 or similar tools for precise genetic corrections.
Targeted Tissue Delivery
Engineered for specific tissue or organ targeting in research and therapy.
Chronic Disease Studies
Provides stable, long-lasting gene expression for studying chronic conditions.
Adenovirus
Vaccine Development
Widely used as vectors in vaccine platforms for infectious diseases like COVID-19.
Transient Gene Expression
Ideal for short-term expression in in vitro and in vivo studies.
Cancer Research
Delivers genes for oncolytic therapy or tumor suppression studies.
Immunotherapy Studies
Serves as a tool for modulating immune responses in research.