human ABCC3 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human ABCC3.
shAAV-200078
AAV-h-ABCC3-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human ABCC3 (ATP binding cassette subfamily C member 3). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
ABC31; cMOAT2; EST90757; MLP2; MOAT-D; MRP3
Description (Vector)
ABCC3 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. The specific function of this protein has not yet been determined; however, this protein may play a role in the transport of biliary and intestinal excretion of organic anions. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized.
Gene ID
8714
Gene Name (Vector)
ATP binding cassette subfamily C member 3
Gene Symbol
ABCC3
HGNC ID
HGNC:54
ORF Size (aa)
4584
ORF Size (bp)
4584 bp
RefSeq ID
NM_003786
RefSeq Synonyms
NM_003786, NM_001144070, BC137348, BC137347,
Species
human
UniGene ID
Hs.463421
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.