human ABCC11 shRNA silencing AAV

Name 
AAV-h-ABCC11-shRNA
Cat No 
shAAV-200073
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human ABCC11.

shAAV-200073
AAV-h-ABCC11-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human ABCC11 (ATP binding cassette subfamily C member 11). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
EWWD; MRP8; WW
Description (Vector)
ABCC11 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This ABC full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. The product of this gene participates in physiological processes involving bile acids, conjugated steroids, and cyclic nucleotides. In addition, a SNP in this gene is responsible for determination of human earwax type. This gene and family member ABCC12 are determined to be derived by duplication and are both localized to chromosome 16q12.1. Multiple alternatively spliced transcript variants have been described for this gene.
Gene ID
85320
Gene Name (Vector)
ATP binding cassette subfamily C member 11
Gene Symbol
ABCC11
HGNC ID
HGNC:14639
ORF Size (aa)
4146
ORF Size (bp)
4146 bp
RefSeq ID
NM_032583
RefSeq Synonyms
NM_145186, NM_033151, NM_032583, BC157084, BC152902, BC039085,
Species
human
UniGene ID
Hs.652267

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.