human ABCA2 shRNA silencing AAV

Name
AAV-h-ABCA2-shRNA

Cat No
shAAV-200045

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human ABCA2.

shAAV-200045

AAV-h-ABCA2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human ABCA2 (ATP binding cassette subfamily A member 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

ABC2

Description (Vector)

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This protein is highly expressed in brain tissue and may play a role in macrophage lipid metabolism and neural development. Two transcript variants encoding different isoforms have been found for this gene.

Gene ID

Gene Name (Vector)

ATP binding cassette subfamily A member 2

Gene Symbol

ABCA2

HGNC ID

HGNC:32

ORF Size (aa)

7401

ORF Size (bp)

7401 bp

RefSeq ID

NM_001606

RefSeq Synonyms

NM_212533, NM_001606, BC172448,

Species

human

UniGene ID

Hs.421202

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.