human AARS2 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human AARS2.
shAAV-200029
AAV-h-AARS2-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human AARS2 (alanyl-tRNA synthetase 2, mitochondrial). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
AARSL; COXPD8; LKENP; MT-ALARS; MTALARS
Description (Vector)
AARS2 belongs to the class-II aminoacyl-tRNA synthetase family. Aminoacyl-tRNA synthetases play critical roles in mRNA translation by charging tRNAs with their cognate amino acids. The encoded protein is a mitochondrial enzyme that specifically aminoacylates alanyl-tRNA. Mutations in this gene are a cause of combined oxidative phosphorylation deficiency 8.
Gene ID
57505
Gene Name (Vector)
alanyl-tRNA synthetase 2, mitochondrial
Gene Symbol
AARS2
HGNC ID
HGNC:21022
ORF Size (aa)
2958
ORF Size (bp)
2958 bp
RefSeq ID
NM_020745
RefSeq Synonyms
NM_020745, BC131728,
Species
human
UniGene ID
Hs.158381
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.