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human CSH2 Over-expression AAV

Name 
AAV-h-CSH2
Cat No 
AAV-206120
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human CSH2.

AAV-206120
AAV-h-CSH2

Ready-to-use AAV expressing Human CSH2 (chorionic somatomammotropin hormone 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CS-2; CSB; GHB1; hCS-B; PL
Description (Vector)
CSH2 is a member of the somatotropin/prolactin family of hormones and plays an important role in growth control. The gene is located at the growth hormone locus on chromosome 17 along with four other related genes in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. Although the five genes share a remarkably high degree of sequence identity, they are expressed selectively in different tissues. Alternative splicing generates additional isoforms of each of the five growth hormones. This particular family member is expressed mainly in the placenta and utilizes multiple transcription initiation sites. Expression of the identical mature proteins for chorionic somatomammotropin hormones 1 and 2 is upregulated during development, while the ratio of 1 to 2 increases by term. Structural and expression differences provide avenues for developmental regulation and tissue specificity.
Gene ID
1443
Gene Name (Vector)
chorionic somatomammotropin hormone 2
Gene Symbol
CSH2
HGNC ID
HGNC:2441
ORF Size (aa)
654
ORF Size (bp)
654 bp
RefSeq ID
NM_020991
RefSeq Synonyms
NM_022645, NM_022644, NM_020991, BC119748, BC035965, BC022044,
Species
human
UniGene ID
Hs.654515

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.