Promotional banner reading 'FALL SAVINGS' with expiry date August 31 on an orange background; features a group of people with orange stacked blocks on the right and discounts for services and catalog products.

human CORO7 Over-expression AAV

Name 
AAV-h-CORO7
Cat No 
AAV-205805
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human CORO7.

AAV-205805
AAV-h-CORO7

Ready-to-use AAV expressing Human CORO7 (coronin 7). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
0610011B16Rik; 70 kDa WD repeat tumor rejection antigen homolog; coronin-7; CRN7; POD1
Description (eCommerce)
CORO7 is a member of the coronin protein family. However, unlike other coronin proteins, it is not an actin-binding protein but rather functions as an F-actin regulator directing anterograde Golgi to endosome transport. CORO7 has two tandem WD-40 domain repeats and localizes to the trans-Golgi network. The protein undergoes K33-linked polyubiquitination via an E3 ligase complex. It is thought to play an essential role in maintenance of Golgi apparatus morphology [taken from NCBI Entrez Gene (Gene ID: 79585)].
Description (Vector)
Coronins, such as CORO7, constitute an evolutionarily conserved family of WD-repeat actin-binding proteins. CORO7 plays a role in Golgi complex morphology and function (Rybakin et al., 2004, 2006 (PubMed 15327992) (PubMed 16905771)).(supplied by OMIM, Mar 2008)
Gene ID
79585
Gene Name (eCommerce)
coronin 7
Gene Name (Vector)
coronin 7
Gene Symbol
CORO7
HGNC ID
HGNC:26161
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2778
ORF Size (bp)
2778 bp
Protein Name (eCommerce)
Coronin-7
RefSeq ID
NM_024535
RefSeq Synonyms
NM_024535, NM_001201473, NM_001201472, BC117291, BC117289,
Research Areas
Cytoskeleton,Golgi Apparatus
Research Areas (Faceted)
cell_biology
Species
human
Target Sentence
CORO7 is a member of the coronin protein family. However, unlike other coronin proteins, it is not an actin-binding protein but rather functions as an F-actin regulator directing anterograde Golgi to endosome transport. CORO7 has two tandem WD-40 domain repeats and localizes to the trans-Golgi network. The protein undergoes K33-linked polyubiquitination via an E3 ligase complex. It is thought to play an essential role in maintenance of Golgi apparatus morphology [taken from NCBI Entrez Gene (Gene ID: 79585)].
UniGene ID
Hs.437957
UniProt ID (eCommerce)
P57737

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.