human COPS6 Over-expression AAV

Name 
AAV-h-COPS6
Cat No 
AAV-205773
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human COPS6.

AAV-205773
AAV-h-COPS6

Ready-to-use AAV expressing Human COPS6 (COP9 signalosome subunit 6). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CSN6; MOV34-34KD
Description (Vector)
COPS6 is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein belongs to translation initiation factor 3 (eIF3) superfamily. It is involved in the regulation of cell cycle and likely to be a cellular cofactor for HIV-1 accessory gene product Vpr.
Gene ID
10980
Gene Name (Vector)
COP9 signalosome subunit 6
Gene Symbol
COPS6
HGNC ID
HGNC:21749
ORF Size (aa)
984
ORF Size (bp)
984 bp
RefSeq ID
NM_006833
RefSeq Synonyms
NM_006833, BC002520,
Species
human
UniGene ID
Hs.15591

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.