rat GZMB Adenovirus

Name 
Ad-r-GZMB
Cat No 
ADV-295082
Availability
4-5 weeks

This is an Adenovirus expressing Mouse Cer1.

ADV-295082
Ad-r-GZMB

Ready-to-use Adenovirus expressing Rat Gzmb (granzyme B). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
RNKP-1
Description (Vector)
This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.
Gene ID
171528
Gene Name (Vector)
granzyme B
Gene Symbol
Gzmb
ORF Size (aa)
741
RefSeq ID
NM_138517
RefSeq Synonyms
NM_138517, BC127475,
Species
rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.