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human CNTF Over-expression AAV

Name 
AAV-h-CNTF
Cat No 
AAV-205635
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human CNTF.

AAV-205635
AAV-h-CNTF

Ready-to-use AAV expressing Human CNTF (ciliary neurotrophic factor). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
HCNTF
Description (Vector)
CNTF is a polypeptide hormone whose actions appear to be restricted to the nervous system where it promotes neurotransmitter synthesis and neurite outgrowth in certain neuronal populations. The protein is a potent survival factor for neurons and oligodendrocytes and may be relevant in reducing tissue destruction during inflammatory attacks. A mutation in this gene, which results in aberrant splicing, leads to ciliary neurotrophic factor deficiency, but this phenotype is not causally related to neurologic disease. A read-through transcript variant composed of the upstream ZFP91 gene and CNTF sequence has been identified, but it is thought to be non-coding. Read-through transcription of ZFP91 and CNTF has also been observed in mouse.
Gene ID
1270
Gene Name (Vector)
ciliary neurotrophic factor
Gene Symbol
CNTF
HGNC ID
HGNC:2169
ORF Size (aa)
603
ORF Size (bp)
603 bp
RefSeq ID
NM_000614
RefSeq Synonyms
NM_000614, BC074964, BC074963, BC069167, BC068030,
Species
human
UniGene ID
Hs.715806

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.