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human CNKSR2 Over-expression AAV

Name 
AAV-h-CNKSR2
Cat No 
AAV-205585
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human CNKSR2.

AAV-205585
AAV-h-CNKSR2

Ready-to-use AAV expressing Human CNKSR2 (connector enhancer of kinase suppressor of Ras 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CNK2; KSR2; MAGUIN
Description (Vector)
CNKSR2 encodes a multidomain protein that functions as a scaffold protein to mediate the mitogen-activated protein kinase pathways downstream from Ras. CNKSR2 product is induced by vitamin D and inhibits apoptosis in certain cancer cells. It may also play a role in ternary complex assembly of synaptic proteins at the postsynaptic membrane and coupling of signal transduction to membrane/cytoskeletal remodeling. Multiple transcript variants encoding different isoforms have been found for this gene.
Gene ID
22866
Gene Name (Vector)
connector enhancer of kinase suppressor of Ras 2
Gene Symbol
CNKSR2
HGNC ID
HGNC:19701
ORF Size (aa)
3105
ORF Size (bp)
3105 bp
RefSeq ID
NM_014927
RefSeq Synonyms
NM_014927, NM_001330773, NM_001330772, NM_001330771, NM_001330770, NM_001168649, NM_001168648, NM_001168647, BC143839, BC136289, BC126121,
Species
human
UniGene ID
Hs.555917

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.