rat PRKRA Adenovirus

Name 
Ad-r-PRKRA
Cat No 
ADV-293947
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Rat Prkra.

ADV-293947
Ad-r-PRKRA

Ready-to-use Adenovirus expressing Rat Prkra (protein activator of interferon induced protein kinase EIF2AK2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
RAX
Description (Vector)
Activates EIF2AK2/PKR in the absence of double stranded RNA (dsRNA), leading to phosphorylation of EIF2S1/EFI2-alpha and inhibition of translation and induction of apoptosis. Required for siRNA production by DICER1 and for subsequent siRNA-mediated post-transcriptional gene silencing. Does not seem to be required for processing of pre-miRNA to miRNA by DICER1.
Gene ID
311130
Gene Name (Vector)
protein activator of interferon induced protein kinase EIF2AK2
Gene Symbol
Prkra
ORF Size (aa)
942
ORF Size (bp)
942 bp
RefSeq ID
NM_001024780
RefSeq Synonyms
NM_001024780, BC097446,
Species
rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.