rat TRIB3 Adenovirus
This is an Adenovirus expressing Rat Trib3.
ADV-293274
Ad-r-TRIB3
Ready-to-use Adenovirus expressing Rat Trib3 (tribbles pseudokinase 3). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
NIPK
Description (Vector)
Disrupts insulin signaling by binding directly to Akt kinases and blocking their activation. May bind directly to and mask the 'Thr-308' phosphorylation site in AKT1. Binds to ATF4 and inhibits its transcriptional activation activity. Interacts with the NF-kappa-B transactivator p65 RELA and inhibits its phosphorylation and thus its transcriptional activation activity. Interacts with MAPK kinases and regulates activation of MAP kinases. May play a role in programmed neuronal cell death but does not appear to affect non-neuronal cells. Does not display kinase activity.
Gene ID
246273
Gene Name (Vector)
tribbles pseudokinase 3
Gene Symbol
Trib3
ORF Size (aa)
1050
ORF Size (bp)
1050 bp
RefSeq ID
NM_144755
RefSeq Synonyms
NM_144755, BC091120,
Species
rat
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.