rat BRMS1 Adenovirus
This is an Adenovirus expressing Rat Brms1.
ADV-293097
Ad-r-BRMS1
Ready-to-use Adenovirus expressing Rat Brms1 (breast cancer metastasis-suppressor 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Description (Vector)
Transcriptional repressor. Down-regulates transcription activation by NF-kappa-B by promoting the deacetylation of RELA at 'Lys-310'. Promotes HDAC1 binding to promoter regions. Down-regulates expression of anti-apoptotic genes that are controlled by NF-kappa-B. Promotes apoptosis in cells that have inadequate adherence to a substrate, a process called anoikis, and may thereby inhibit metastasis. May be a mediator of metastasis suppression in breast carcinoma.
Gene ID
293668
Gene Name (Vector)
breast cancer metastasis-suppressor 1
Gene Symbol
Brms1
ORF Size (aa)
741
RefSeq ID
NM_001009605
RefSeq Synonyms
NM_001009605, BC088469,
Species
rat
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.