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human CHRND Over-expression AAV

Name 
AAV-h-CHRND
Cat No 
AAV-205229
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human CHRND.

AAV-205229
AAV-h-CHRND

Ready-to-use AAV expressing Human CHRND (cholinergic receptor nicotinic delta subunit). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
ACHRD; CMS2A; CMS3A; CMS3B; CMS3C; FCCMS; SCCMS
Description (Vector)
The acetylcholine receptor of muscle has 5 subunits of 4 different types: 2 alpha and 1 each of beta, gamma and delta subunits. After acetylcholine binding, the receptor undergoes an extensive conformation change that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. Defects in this gene are a cause of multiple pterygium syndrome lethal type (MUPSL), congenital myasthenic syndrome slow-channel type (SCCMS), and congenital myasthenic syndrome fast-channel type (FCCMS). Several transcript variants, some protein-coding and some not, have been found for this gene.
Gene ID
1144
Gene Name (Vector)
cholinergic receptor nicotinic delta subunit
Gene Symbol
CHRND
HGNC ID
HGNC:1965
ORF Size (aa)
1554
ORF Size (bp)
1554 bp
RefSeq ID
NM_000751
RefSeq Synonyms
NM_001311196, NM_001311195, NM_001256657, NM_000751, BC093925, BC093923,
Species
human
UniGene ID
Hs.156289

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.