rat MKRN1 Adenovirus

Name 
Ad-r-MKRN1
Cat No 
ADV-291999
Availability
4-5 weeks

This is an Adenovirus expressing Rat Mkrn1.

ADV-291999
Ad-r-MKRN1

Ready-to-use Adenovirus expressing Rat Mkrn1 (makorin ring finger protein 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Description (Vector)
E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. These substrates include FILIP1, p53/TP53, CDKN1A and TERT. Keeps cells alive by suppressing p53/TP53 under normal conditions, but stimulates apoptosis by repressing CDKN1A under stress conditions. Acts as a negative regulator of telomerase. Has negative and positive effects on RNA polymerase II-dependent transcription.
Gene ID
296988
Gene Name (Vector)
makorin ring finger protein 1
Gene Symbol
Mkrn1
ORF Size (aa)
990
ORF Size (bp)
990 bp
RefSeq ID
NM_001004233
RefSeq Synonyms
NM_001004233, BC079407,
Species
rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.