rat UBE2A Adenovirus

Name
Ad-r-UBE2A

Cat No
ADV-291785

Availability
4-5 weeks

This is an Adenovirus expressing Rat Ube2a.

ADV-291785

Ad-r-UBE2A

Ready-to-use Adenovirus expressing Rat Ube2a (ubiquitin-conjugating enzyme E2A). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Description (Vector)

Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In association with the E3 enzyme BRE1 (RNF20 and/or RNF40), it plays a role in transcription regulation by catalyzing the monoubiquitination of histone H2B at 'Lys-120' to form H2BK120ub1. H2BK120ub1 gives a specific tag for epigenetic transcriptional activation, elongation by RNA polymerase II, telomeric silencing, and is also a prerequisite for H3K4me and H3K79me formation. In vitro catalyzes 'Lys-11', as well as 'Lys-48'-linked polyubiquitination. Required for postreplication repair of UV-damaged DNA.

Gene ID

298317

Gene Name (Vector)

ubiquitin-conjugating enzyme E2A

Gene Symbol

Ube2a

ORF Size (aa)

489

ORF Size (bp)

489 bp

RefSeq ID

NM_001013933

RefSeq Synonyms

NM_001013933, BC079353,

Species

rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.