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human CHD1L Over-expression AAV

Name 
AAV-h-CHD1L
Cat No 
AAV-205111
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human CHD1L.

AAV-205111
AAV-h-CHD1L

Ready-to-use AAV expressing Human CHD1L (chromodomain helicase DNA binding protein 1 like). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
ALC1; amplified in liver cancer 1; amplified in liver cancer protein 1; CHDL; chromodomain-helicase-DNA-binding protein 1-like
Description (eCommerce)
Chromodomain-helicase-DNA-binding protein 1-like (CHD1L) is a DNA helicase which plays a role in chromatin-remodeling following DNA damage. CHD1L is targeted to sites of DNA damage through interaction with poly(ADP-ribose) and functions to regulate chromatin during DNA repair. It is able to catalyze nucleosome sliding in an ATP-dependent manner, and its helicase activity is strongly stimulated upon poly(ADP-ribose)-binding [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q86WJ1].
Description (Vector)
CHD1L encodes a DNA helicase protein involved in DNA repair. The protein converts ATP to add poly(ADP-ribose) as it regulates chromatin relaxation following DNA damage. Several alternatively spliced transcripts variants have been described for this gene.
Gene ID
9557
Gene Name (eCommerce)
chromodomain helicase DNA binding protein 1 like
Gene Name (Vector)
chromodomain helicase DNA binding protein 1 like
Gene Symbol
CHD1L
HGNC ID
HGNC:1916
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2082
ORF Size (bp)
2082 bp
Protein Name (eCommerce)
Chromodomain-helicase-DNA-binding protein 1-like
RefSeq ID
NM_004284
RefSeq Synonyms
NM_024568, NM_004284, NM_001256338, NM_001256337, NM_001256336, BC077717,
Research Areas
Chromatin Remodeling,DNA Damage/Repair,Helicase Activity
Research Areas (Faceted)
cell_biology,genetics,transcription_translation
Species
human
Target Sentence
Chromodomain-helicase-DNA-binding protein 1-like (CHD1L) is a DNA helicase which plays a role in chromatin-remodeling following DNA damage. CHD1L is targeted to sites of DNA damage through interaction with poly(ADP-ribose) and functions to regulate chromatin during DNA repair. It is able to catalyze nucleosome sliding in an ATP-dependent manner, and its helicase activity is strongly stimulated upon poly(ADP-ribose)-binding [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q86WJ1].
UniGene ID
Hs.191164
UniProt ID (eCommerce)
Q86WJ1

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.