rat NDEL1 Adenovirus
This is an Adenovirus expressing Mouse Adcy2.
ADV-290655
Ad-r-NDEL1
Ready-to-use Adenovirus expressing Rat Ndel1 (nudE neurodevelopment protein 1-like 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
NUDE2; Nudel
Description (Vector)
Required for organization of the cellular microtubule array and microtubule anchoring at the centrosome. May regulate microtubule organization at least in part by targeting the microtubule severing protein KATNA1 to the centrosome. Also positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus ends. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the centripetal motion of secretory vesicles and the coupling of the nucleus and centrosome. Also required during brain development for the migration of newly formed neurons from the ventricular/subventricular zone toward the cortical plate. Plays a role, together with DISC1, in the regulation of neurite outgrowth. Required for mitosis in some cell types but appears to be dispensible for mitosis in cortical neuronal progenitors, which instead requires NDE1. Facilitates the polymerization of neurofilaments from the individual subunits NEFH and NEFL.
Gene ID
170845
Gene Name (Vector)
nudE neurodevelopment protein 1-like 1
Gene Symbol
Ndel1
ORF Size (aa)
987
RefSeq ID
NM_133320
RefSeq Synonyms
NM_133320, BC070909,
Species
rat
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.