mouse MAPK7 Adenovirus
This is an Adenovirus expressing Mouse 6430531B16Rik.
ADV-280873
Ad-m-MAPK7
Ready-to-use Adenovirus expressing Mouse Mapk7 (mitogen-activated protein kinase 7). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
BMK-1; BMK1; ERK-5; ERK5; Erk5-T; PRKM7
Description (Vector)
Plays a role in various cellular processes such as proliferation, differentiation and cell survival. The upstream activator of MAPK7 is the MAPK kinase MAP2K5. Upon activation, it translocates to the nucleus and phosphorylates various downstream targets including MEF2C. EGF activates MAPK7 through a Ras-independent and MAP2K5-dependent pathway. May have a role in muscle cell differentiation. May be important for endothelial function and maintenance of blood vessel integrity. MAP2K5 and MAPK7 interact specifically with one another and not with MEK1/ERK1 or MEK2/ERK2 pathways. Phosphorylates SGK1 at Ser-78 and this is required for growth factor-induced cell cycle progression.
Gene ID
23939
Gene Name (Vector)
mitogen-activated protein kinase 7
Gene Symbol
Mapk7
ORF Size (aa)
2271
ORF Size (bp)
2271 bp
RefSeq ID
NM_011841
RefSeq Synonyms
NM_011841, NM_001291037, NM_001291036, NM_001291035, NM_001291034, NM_001291033, BC100398,
Species
mouse
UniGene ID
Mm.38172
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.