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human CDH4 Over-expression AAV

Name 
AAV-h-CDH4
Cat No 
AAV-204825
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human CDH4.

AAV-204825
AAV-h-CDH4

Ready-to-use AAV expressing Human CDH4 (cadherin 4). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CAD4; R-CAD; RCAD
Description (Vector)
CDH4 is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Based on studies in chicken and mouse, this cadherin is thought to play an important role during brain segmentation and neuronal outgrowth. In addition, a role in kidney and muscle development is indicated. Of particular interest are studies showing stable cis-heterodimers of cadherins 2 and 4 in cotransfected cell lines. Previously thought to interact in an exclusively homophilic manner, this is the first evidence of cadherin heterodimerization. Three transcript variants encoding different isoforms have been found for this gene.
Gene ID
1002
Gene Name (Vector)
cadherin 4
Gene Symbol
CDH4
HGNC ID
HGNC:1763
ORF Size (aa)
2751
ORF Size (bp)
2751 bp
RefSeq ID
NM_001794
RefSeq Synonyms
NM_001794, NM_001252339, NM_001252338, BC112150, BC101651,
Species
human
UniGene ID
Hs.598638

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.