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mouse DNMT3L Adenovirus

Name 
Ad-m-DNMT3L
Cat No 
ADV-280690
Availability
4-5 weeks

This is an Adenovirus expressing Mouse Dnmt3l.

ADV-280690
Ad-m-DNMT3L

Ready-to-use Adenovirus expressing Mouse Dnmt3l (DNA (cytosine-5-)-methyltransferase 3-like). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
D6Ertd14e; ecat7
Description (Vector)
Catalytically inactive regulatory factor of DNA methyltransferases. It is essential for the function of DNMT3A and DNMT3B. Activates DNMT3A and DNMT3B by binding to their catalytic domain. Accelerates the binding of DNA and AdoMet to the methyltransferases and dissociates from the complex after DNA binding to the methyltransferases. Recognizes unmethylated histone H3 lysine 4 (H3K4) and induces de novo DNA methylation by recruitment or activation of DNMT3.
Gene ID
54427
Gene Name (Vector)
DNA (cytosine-5-)-methyltransferase 3-like
Gene Symbol
Dnmt3l
ORF Size (aa)
1266
ORF Size (bp)
1266 bp
RefSeq ID
NM_019448
RefSeq Synonyms
NM_019448, NM_001284200, NM_001284199, NM_001284198, NM_001284197, NM_001081695, BC083147,
Species
mouse
UniGene ID
Mm.13433

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.