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human CDC42EP3 Over-expression AAV

Name 
AAV-h-CDC42EP3
Cat No 
AAV-204767
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human CDC42EP3.

AAV-204767
AAV-h-CDC42EP3

Ready-to-use AAV expressing Human CDC42EP3 (CDC42 effector protein 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
binder of Rho GTPases 2; BORG2; CDC42 effector protein (Rho GTPase binding) 3; cdc42 effector protein 3; CEP3; CRIB-containing BORG2 protein; MSE55-related Cdc42-binding protein; MSE55-related protein; UB1
Description (eCommerce)
BORG2 (binder of Rho GTPases 2) is a member of a family of proteins that bind the TC10 and Cdc42 GTPases in a GTP-dependent manner. BORG family members have been shown to play a role in the regulation of septin assembly and organization.
Description (Vector)
CDC42EP3 encodes a member of a small family of guanosine triphosphate (GTP) metabolizing proteins that contain a CRIB (Cdc42, Rac interactive binding) domain. Members of this family of proteins act as effectors of CDC42 function. The encoded protein is involved in actin cytoskeleton re-organization during cell shape changes, including pseudopodia formation. A pseudogene of this gene is found on chromosome 19. Alternative splicing results in multiple transcript variants.
Gene ID
10602
Gene Name (eCommerce)
CDC42 effector protein 3
Gene Name (Vector)
CDC42 effector protein 3
Gene Symbol
CDC42EP3
HGNC ID
HGNC:16943
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
765
ORF Size (bp)
765 bp
Protein Name (eCommerce)
Cdc42 effector protein 3
RefSeq ID
NM_006449
RefSeq Synonyms
NM_006449, NM_001270438, NM_001270437, NM_001270436, BC019270,
Research Areas
Cytoskeleton,Neurobiology,Signal Transduction
Research Areas (Faceted)
signal_transduction,cell_biology,neurobiology
Species
human
Target Sentence
BORG2 (binder of Rho GTPases 2) is a member of a family of proteins that bind the TC10 and Cdc42 GTPases in a GTP-dependent manner. BORG family members have been shown to play a role in the regulation of septin assembly and organization.
UniGene ID
Hs.369574
UniProt ID (eCommerce)
Q9UKI2

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.