mouse XPO4 Adenovirus
This is an Adenovirus expressing Mouse Xpo4.
ADV-276410
Ad-m-XPO4
Ready-to-use Adenovirus expressing Mouse Xpo4 (exportin 4). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
B430309A01Rik; mKIAA1721
Description (Vector)
Mediates the nuclear export of proteins (cargos) with broad substrate specificity. In the nucleus binds cooperatively to its cargo and to the GTPase Ran in its active GTP-bound form. Docking of this trimeric complex to the nuclear pore complex (NPC) is mediated through binding to nucleoporins. Upon transit of a nuclear export complex into the cytoplasm, disassembling of the complex and hydrolysis of Ran-GTP to Ran-GDP (induced by RANBP1 and RANGAP1, respectively) cause release of the cargo from the export receptor. XPO4 then return to the nuclear compartment and mediate another round of transport. The directionality of nuclear export is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus.
Gene ID
57258
Gene Name (Vector)
exportin 4
Gene Symbol
Xpo4
ORF Size (aa)
3456
ORF Size (bp)
3456 bp
RefSeq ID
NM_020506
RefSeq Synonyms
NM_020506, BC156636,
Species
mouse
UniGene ID
Mm.202747
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.