mouse WRAP53 Adenovirus

Name 
Ad-m-WRAP53
Cat No 
ADV-276336
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Mouse Wrap53.

ADV-276336
Ad-m-WRAP53

Ready-to-use Adenovirus expressing Mouse Wrap53 (WD repeat containing, antisense to Trp53). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
BC021790; Wdr79
Description (Vector)
Essential component of the telomerase holoenzyme complex, a ribonucleoprotein complex essential for the replication of chromosome termini that elongates telomeres in most eukaryotes. In the telomerase holoenzyme complex, it controls telomerase localization to Cajal body. Required for delivery of TERC to telomeres during S phase and for telomerase activity. Binds small Cajal body RNAs (scaRNAs). The mRNA encoding this protein plays a critical role in the regulation of p53 expression at the post-transcriptional level; it is involved both in maintaining basal p53 mRNA levels and in p53 induction upon DNA damage.
Gene ID
216853
Gene Name (Vector)
WD repeat containing, antisense to Trp53
Gene Symbol
Wrap53
ORF Size (aa)
1599
ORF Size (bp)
1599 bp
RefSeq ID
NM_144824
RefSeq Synonyms
NM_144824, BC069868, BC021790,
Species
mouse
UniGene ID
Mm.31586

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.