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human CD1B Over-expression AAV

Name 
AAV-h-CD1B
Cat No 
AAV-204590
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human CD1B.

AAV-204590
AAV-h-CD1B

Ready-to-use AAV expressing Human CD1B (CD1b molecule). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CD1; CD1A; R1
Description (Vector)
CD1B encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail, and requires vesicular acidification to bind lipid antigens.
Gene ID
910
Gene Name (Vector)
CD1b molecule
Gene Symbol
CD1B
HGNC ID
HGNC:1635
ORF Size (aa)
1002
ORF Size (bp)
1002 bp
RefSeq ID
NM_001764
RefSeq Synonyms
NM_001764, BC104217, BC104216, BC074747, BC069481,
Species
human
UniGene ID
Hs.1310

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.